The average strength of the garrison on 25 Feb 1830 was 2,721 rank and file.
On 18 Feb 1830, smallpox was brought to Malta from Greece on HMS Asia. It spread rapidly throughout the island, despite the imposition of quarantine. The majority of the civilians had not been vaccinated, so that by 1 July, there were 1,274 infected, with 144 deaths. Between Mar 1830 and Aug 1831, smallpox attacked 8,067 Maltese and 2,284 Gozitans. There were 1,172 deaths in Malta and 351 in Gozo, a total of 1,523, or 1:68 of those attacked out of a total population in Malta of 105,367.
The following christening was recorded in 1830:
William Richardson born on 15 Dec 1829, son of Benjamin Richardson, Clerk in the Military Medical Department and his wife Sarah, was baptised on 20 Jan 1830.
The following burials were recorded in 1830:
- 15 Jan: Gnr Thomas Admead Marine Artillery HM Bomb Cerberus.
- 16 Jan: Assistant Surgeon A. J. Weinzierl, 27 years, Dutch Navy.
- 16 Jan: Seamen John Russell, HMS Revenge.
- 26 Jan: Yeoman Thomas Jones, HMS Britannia.
- 30 Jan: Isaac Nilson, a Swedish seaman died in the Civil Hospital.
- 13 Feb: Gnr John Moore, HMS Ocean.
- 14 Feb: Thomas Hanies, 35 years died in the Civil Hospital.
- 22 Mar: Pte Marine Thomas Hughes HMS Asia.
- 24 Mar: Thomas Matherall HMS Britannia.
- 16 Apr: Clerk Thomas Andrews, 25 years, HMS Samarany.
- 22 Apr: Able Seaman John Fier, 25 years, HMS Samarany.
- 3 May: Thomas Sparks, HMS Britannia.
- 30 May: Seaman John Burrow, HMS Britannia.
- 5 June: Sail Master Gibbons Pemberton, 34 years, HMS Weazle.
- 19 June: Thomas Knight, HMS Melville.
- 11 July: Pte Marine William Knight, HMS Favorite.
- 11 July: Isaac Thorndike, 22 years, an American seaman, died in the Civil Hospital.
- 18 July: Purser Thomas Harding, HMS Favorite.
- 28 July: Able Seaman John Menay, HMS Britannia.
- 2 Aug: Captain John Cole, HMS Gloucester.
- 15 Sept: Pte Marine John Pain, 40 years, HMS Pelican.
- 25 Sept: John Warrell, Shipwright in the Dock Yard.
- 21 Oct: Jane Eliza Dombre, born on 2 Dec 1829, aged 10 months, daughter of Lt Jean David Dombre half pay De Meuron Regiment and his wife Marie Elise Bornand.
- 29 Oct: Capt's Mate Robert Fowler, 44 years, HMS Madagascar.
- 31 Oct: Seaman William Clifton, HMS Windsor Castle.
- 24 Nov: Pte Marine Peter Ferguson, 30 years, HMS Windsor Castle.
- 10 Dec: James Toole, 52 years, half-pay Deputy Commissary General.
- 12 Dec: The Hon Sir Robert Spencer, 39 years, Capt HMS Madagascar.